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1

Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab

Lee, Hyun Tae, Lee, Ju Yeon, Lim, Heejin, Lee, Sang Hyung, Moon, Yu Jeong, Pyo, Hyo Jeong, Ryu, Seong Eon, Shin, Woori, Heo, Yong-Seok

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.19 MB

english, 2017

2

A DIELECTRIC PROPERTY ANALYSIS OF FERROELECTRIC THIN FILM USING TERAHERTZ TIME-DOMAIN SPECTROSCOPY

RYU, HAN-CHEOL, KWAK, MIN-HWAN, KANG, SEUNG-BEOM, JEONG, SE-YOUNG, PAEK, MUN-CHEOL, KANG, KWANG-YONG, LEE, SU-JAE, MOON, SEUNG EON, PARK, SEONG-OOK

Journal:

Integrated Ferroelectrics

Year:

2007

Language:

english

File:

PDF, 740 KB

english, 2007

3

BetaVoid: Molecular voids via beta-complexes and Voronoi diagrams

Kim, Jae-Kwan, Cho, Youngsong, Laskowski, Roman A, Ryu, Seong Eon, Sugihara, Kokichi, Kim, Deok-Soo

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2014

Language:

english

File:

PDF, 1.85 MB

english, 2014

4

Identification of novel protein tyrosine phosphatase sigma inhibitors promoting neurite extension

Lee, Hye Seon, Ku, Bonsu, Park, Tae Hyun, Park, Hwangseo, Choi, Joong-Kwon, Chang, Kyu-Tae, Kim, Cheol-Hee, Ryu, Seong Eon, Kim, Seung Jun

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 1.65 MB

english, 2016

5

MGOS: A library for molecular geometry and its operating system

Kim, Deok-Soo, Ryu, Joonghyun, Cho, Youngsong, Lee, Mokwon, Cha, Jehyun, Song, Chanyoung, Kim, Sang Wha, Laskowski, Roman A., Sugihara, Kokichi, Bhak, Jong, Ryu, Seong Eon

Journal:

Computer Physics Communications

Year:

2020

File:

PDF, 4.79 MB

2020

6

Crystallization and preliminary X-ray crystallographic studies of ketosteroid isomerase fromPseudomonas putida biotype B

Oh, Byung-Ha, Kim, Suhng Wook, Ryu, Seong-Eon, Kim, Sang-Soo, Yoon, Mi-Kyung, Choi, Kwan Yong

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1996

Language:

english

File:

PDF, 235 KB

english, 1996

7

Enhanced chondrogenic marker expression of human mesenchymal stem cells by interaction with both TGF-β3 and hyaluronic acid

Suk Ho Bhang, Jeong-Yi Jeon, Wan-Geun La, Jun Yeup Seong, Jin Wook Hwang, Seong Eon Ryu, Byung-Soo Kim

Journal:

Biotechnology and Applied Biochemistry

Year:

2011

Language:

english

File:

PDF, 331 KB

english, 2011

8

ChemInform Abstract: Identification of Two Novel VHR Phosphatase Inhibitors with Structure-Based Virtual Screening.

Hwangseo Park, Jeong-Yi Jeon, Dae-Gwin Jeong, Seong Eon Ryu

Journal:

Year:

2011

File:

PDF, 22 KB

2011

9

ChemInform Abstract: Discovery of Novel Inhibitors of Dual-Specificity Phosphatase Pyst2 with Structure-Based Virtual Screening.

Hwangseo Park, Jeong-Yi Jeon, Seong Eon Ryu, Seung Jun Kim

Journal:

Year:

2011

File:

PDF, 21 KB

2011

10

Discovery of VHR Phosphatase Inhibitors with Micromolar Activity based on Structure-Based Virtual Screening

Hwangseo Park, Suk-Kyeong Jung, Dae Gwin Jeong, Seong Eon Ryu, Seung Jun Kim

Journal:

Year:

2008

Language:

english

File:

PDF, 257 KB

english, 2008

11

Protein tyrosine phosphatase 1B inhibitors from Morus root bark

Long Cui, MinKyun Na, Hyuncheol Oh, Eun Young Bae, Dae Gwin Jeong, Seong Eon Ryu, Sohee Kim, Bo Yeon Kim, Won Keun Oh, Jong Seog Ahn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 114 KB

english, 2006

12

Discovery of novel PRL-3 inhibitors based on the structure-based virtual screening

Hwangseo Park, Suk-Kyeong Jung, Dae Gwin Jeong, Seong Eon Ryu, Seung Jun Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 706 KB

english, 2008

13

Identification of novel inhibitors of extracellular signal-regulated kinase 2 based on the structure-based virtual screening

Hwangseo Park, Young Jae Bahn, Dae Gwin Jeong, Eui Jeon Woo, Jung Sun Kwon, Seong Eon Ryu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 451 KB

english, 2008

14

Structure-based de novo design and biochemical evaluation of novel Cdc25 phosphatase inhibitors

Hwangseo Park, Young Jae Bahn, Seong Eon Ryu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 2.57 MB

english, 2009

15

Phosphoproteomic analysis of neuronal cell death by glutamate-induced oxidative stress

Tae Hyuk Kang, Kwang-Hee Bae, Min-jung Yu, Won-Kon Kim, Hyang-Ran Hwang, Hyeyun Jung, Phil Young Lee, Sunghyun Kang, Tae-Sung Yoon, Sung Goo Park, Seong Eon Ryu, Sang Chul Lee

Journal:

Year:

2007

Language:

english

File:

PDF, 495 KB

english, 2007

16

Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase

Tae-Sung Yoon, Dae Gwin Jeong, Jae Hoon Kim, Yoon Hea Cho, Jeong Hee Son, Ji Won Lee, Seong Eon Ryu, Seung Jun Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2005

Language:

english

File:

PDF, 185 KB

english, 2005

17

Crystal structure of human TMDP, a testis-specific dual specificity protein phosphatase: Implications for substrate specificity

Seung Jun Kim, Dae-Gwin Jeong, Tae-Sung Yoon, Jeong-Hee Son, Somi Kim Cho, Seong Eon Ryu, Jae-Hoon Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 478 KB

english, 2007

18

Crystal structure of the catalytic domain of human DUSP5, a dual specificity MAP kinase protein phosphatase

Dae Gwin Jeong, Yoon Hea Cho, Tae-Sung Yoon, Jae Hoon Kim, Seong Eon Ryu, Seung Jun Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 400 KB

english, 2007

19

Crystal structure of human slingshot phosphatase 2

Suk-Kyeong Jung, Dae Gwin Jeong, Tae-Sung Yoon, Jae Hoon Kim, Seong Eon Ryu, Seung Jun Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2007

Language:

english

File:

PDF, 736 KB

english, 2007

20

Structural basis for the cold adaptation of psychrophilic M37 lipase from Photobacterium lipolyticum

Suk-Kyeong Jung, Dae Gwin Jeong, Mi Sook Lee, Jung-Kee Lee, Hyung-Kwoun Kim, Seong Eon Ryu, Byoung Chul Park, Jae Hoon Kim, Seung Jun Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2008

Language:

english

File:

PDF, 571 KB

english, 2008

21

Crystal structure of the catalytic domain of human MKP-2 reveals a 24-mer assembly

Dae Gwin Jeong, Suk-Kyeong Jung, Tae-Sung Yoon, Eui-Jeon Woo, Jae Hoon Kim, Byoung Chul Park, Seong Eon Ryu, Seung Jun Kim

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2009

Language:

english

File:

PDF, 125 KB

english, 2009

22

Crystal structure of a novel mitogen-activated protein kinase phosphatase, SKRP1

Chun Hua Wei, Sun Young Ryu, Young Ho Jeon, Moon Young Yoon, Dae Gwin Jeong, Seung Jun Kim, Seong Eon Ryu

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2011

Language:

english

File:

PDF, 592 KB

english, 2011

23

Identification of novel inhibitors of mitogen-activated protein kinase phosphatase-1 with structure-based virtual screening

Hwangseo Park, Jeong-Yi Jeon, Song Yi Kim, Dae Gwin Jeong, Seong Eon Ryu

Journal:

Journal of Computer-Aided Molecular Design

Year:

2011

Language:

english

File:

PDF, 370 KB

english, 2011

24

Origin of the stereospecificity in binding hydroxamates of α- and β-phenylalanine methylamide to thermolysin revealed by the X-ray crystallographic study

Seung-Jun Kim, Dong H Kim, Jung Dae Park, Joo-Rang Woo, Yonghao Jin, Seong Eon Ryu

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 266 KB

english, 2003

25

Crystal structure of an HIV-binding recombinant fragment of human CD4

Ryu, Seong-Eon, Kwong, Peter D., Truneh, Alemseged, Porter, Terence G., Arthos, James, Rosenberg, Martin, Dai, Xiaoping, Xuong, Nguyen-huu, Axel, Richard, Sweet, Raymond W.

Journal:

Year:

1990

File:

PDF, 1.33 MB

1990

26

10.1038/87639

Kim, Seung-Jun, Jeong, Dae-Gwin, Chi, Seung-Wook, Lee, Jin-Sook, Ryu, Seong-Eon

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 4.30 MB

english, 2001

27

Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn

Lim, So-Hee, Kwon, Seok-Kyu, Lee, Myung Kyu, Moon, Jeonghee, Jeong, Dae Gwin, Park, Eunha, Kim, Seung Jun, Park, Byung Chul, Lee, Sang Chul, Ryu, Seong-Eon

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 3.38 MB

english, 2009

28

Crystal structure of a novel human peroxidase enzyme at 2.0 Å resolution

Choi, Hee-Jeong, Kang, Sang Won, Yang, Chul-Hak, Rhee, Sue Goo, Ryu, Seong-Eon

Journal:

Natural Structural Biology

Year:

1998

File:

PDF, 1.17 MB

1998

29

Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path

Lee, Cheolju, Lee, Soon Mi, Mukhopadhyay, Partha, Kim, Seung Jun, Lee, Sang Chul, Ahn, Woo-Sung, Yu, Myeong-Hee, Storz, Gisela, Ryu, Seong Eon

Journal:

Nature Structural and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 444 KB

english, 2004

30

Homology modeling of the receptor binding domain of human thrombopoietin

Jin-Soo Song, Heungrok Park, Hyo-Jeong Hong, Myeong-Hee Yu, Seong-Eon Ryu

Journal:

Journal of Computer-Aided Molecular Design

Year:

1998

Language:

english

File:

PDF, 97 KB

english, 1998

31

Vacuolar (H+)-ATPases in Caenorhabditis elegans: What can we learn about giant H+ pumps from tiny worms?

Sun-Kyung Lee, Weixun Li, Seong-Eon Ryu, TaiYoun Rhim, Joohong Ahnn

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2010

Language:

english

File:

PDF, 628 KB

english, 2010

32

Emodin inhibits migration and invasion of DLD-1 (PRL-3) cells via inhibition of PRL-3 phosphatase activity

Young-Min Han, Su-Kyung Lee, Dae Gwin Jeong, Seong Eon Ryu, Dong Cho Han, Dae Keun Kim, Byoung-Mog Kwon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 774 KB

english, 2012

33

Structure-based virtual screening approach to the discovery of novel PTPMT1 phosphatase inhibitors

Hwangseo Park, Song Yi Kim, Ayoung Kyung, Tae-sung Yoon, Seong Eon Ryu, Dae Gwin Jeong

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

34

Broadly neutralizing anti-HBV antibody binds to non-epitope regions of preS1

Seung-Wook Chi, Jinki Kim, Gwan-Su Yi, Hyo Jeong Hong, Seong Eon Ryu

Journal:

Year:

2009

Language:

english

File:

PDF, 539 KB

english, 2009

35

Structural mechanism of the antigen recognition by the L1 cell adhesion molecule antibody A10-A3

Chun Hua Wei, Eung Suk Lee, Jeong Yi Jeon, Yong-Seok Heo, Seung Jun Kim, Young Ho Jeon, Kyung Hyun Kim, Hyo Jeong Hong, Seong Eon Ryu

Journal:

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

36

Crystal structure of constitutively monomeric E. coli Hsp33 mutant with chaperone activity

Seung-Wook Chi, Dae Gwin Jeong, Joo Rang Woo, Hye Seon Lee, Byoung Cheol Park, Bo Yeon Kim, Raymond L. Erikson, Seong Eon Ryu, Seung Jun Kim

Journal:

Year:

2011

Language:

english

File:

PDF, 1.39 MB

english, 2011

37

Cretaceous epithermal gold–silver mineralization and geodynamic environment, Korea

Seon-Gyu Choi, In-Chang Ryu, Sang Joon Pak, Soo-Meen Wee, Chang Seong Kim, Maeng-Eon Park

Journal:

Ore Geology Reviews

Year:

2005

Language:

english

File:

PDF, 827 KB

english, 2005

38

Structures of an HIV and MHC binding fragment from human CD4 as refined in two crystal lattices

Seong-Eon Ryu, Alemseged Truneh, Raymond W Sweet, Wayne A Hendrickson

Journal:

Year:

1994

Language:

english

File:

PDF, 1.94 MB

english, 1994

39

The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved α1-antitrypsin at 2.7 å

Seong-Eon Ryu, Hee-Jeong Choi, Ki-Sun Kwon, Kee Nyung Lee, Myeong-Hee Yu

Journal:

Year:

1996

Language:

english

File:

PDF, 1.09 MB

english, 1996

40

Effects of Metal Ions on the Activity of Protein Tyrosine Phosphatase VHR: Highly Potent and Reversible Oxidative Inactivation by Cu2+ Ion

Jin-Hahn Kim, Hyeongjin Cho, Seong-Eon Ryu, Myung-Un Choi

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 253 KB

english, 2000

41

A 2.1 Å resolution structure of an uncleaved α1-antitrypsin shows variability of the reactive center and other loops

Seung-Jun Kim, Joo-Rang Woo, Eun Joo Seo, Myeong-Hee Yu, Seong-Eon Ryu

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 749 KB

english, 2001

42

Production of hepatitis B virus preS polypeptide in Escherichia coli by mutation of the 5′-end coding sequence and its purification and characterization

Hee Sun Kim, Youn Kyu Kim, Seong-Eon Ryu, Hyo Jeong Hong

Journal:

Year:

1996

Language:

english

File:

PDF, 433 KB

english, 1996

43

NSC-87877, inhibitor of SHP-1/2 PTPs, inhibits dual-specificity phosphatase 26 (DUSP26)

Mina Song, Jae Eun Park, Sung Goo Park, Do Hee Lee, Hyung-Kyoon Choi, Byoung Chul Park, Seong Eon Ryu, Jae Hoon Kim, Sayeon Cho

Journal:

Biochemical and Biophysical Research Communications

Year:

2009

Language:

english

File:

PDF, 315 KB

english, 2009

44

Trimeric Structure of PRL-1 Phosphatase Reveals an Active Enzyme Conformation and Regulation Mechanisms

Dae Gwin Jeong, Seung Jun Kim, Jae Hoon Kim, Jeong Hee Son, Mi Rim Park, Sang Myoun Lim, Tae-Sung Yoon, Seong Eon Ryu

Journal:

Journal of Molecular Biology

Year:

2005

Language:

english

File:

PDF, 865 KB

english, 2005

45

Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase

Dae Gwin Jeong, Tae-Sung Yoon, Jae Hoon Kim, Mi Young Shim, Suk-Kyeong Jung, Jeong Hee Son, Seong Eon Ryu, Seung Jun Kim

Journal:

Journal of Molecular Biology

Year:

2006

Language:

english

File:

PDF, 830 KB

english, 2006

46

Structural Insight into the Constitutive Repression Function of the Nuclear Receptor Rev-erbβ

Eui-Jeon Woo, Dae Gwin Jeong, Mi-Youn Lim, Seung Jun Kim, Kyung-Jin Kim, Sei-Mee Yoon, Byoung-Chul Park, Seong Eon Ryu

Journal:

Journal of Molecular Biology

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

47

Binding and regulation of HIF-1α by a subunit of the proteasome complex, PSMA7

Sayeon Cho, Youn-Jeong Choi, Jeong-Min Kim, Seong-Tae Jeong, Jae-Hoon Kim, Seung-Ho Kim, Seong-Eon Ryu

Journal:

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

48

Crystal structure of DsbDγ reveals the mechanism of redox potential shift and substrate specificity

Jae Hoon Kim, Seung Jun Kim, Dae Gwin Jeong, Jeong Hee Son, Seong Eon Ryu

Journal:

Year:

2003

Language:

english

File:

PDF, 466 KB

english, 2003

49

Structural Basis of the Redox Switch in the OxyR Transcription Factor

Hee-Jung Choi, Seung-Jun Kim, Partha Mukhopadhyay, Sayeon Cho, Joo-Rang Woo, Gisela Storz, Seong-Eon Ryu

Journal:

Year:

2001

Language:

english

File:

PDF, 1014 KB

english, 2001

50

Structure and design of broadly-neutralizing antibodies against HIV

Seong Eon Ryu, Wayne A. Hendrickson

Journal:

Molecules and Cells

Year:

2012

Language:

english

File:

PDF, 568 KB

english, 2012